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I pazienti che hanno utilizzato il sildenafil, non vi era alcuna differenza profilo di effetti collaterali rispetto al placebo, mentre l'applicazione di tali classi di farmaci antipertensivi come i diuretici, beta-bloccanti, ACE-inibitori, antagonisti dell'angiotensina II, prodotti medicinali antipertensivi (vasodilatatori e ad azione. Sildenafil ha azione vasodilatatrice che appare riduzione facile e breve termine della pressione sanguigna.
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